It contains quality fish oil for the all-important DHA and EPA fatty acids. The fish oil used comes from fish that stores the fat in the body (not fish liver oil). The fish oil used is Reviact™ Multi Omega is menhaden fish oil, an omega-3 rich fish harvested in the federally regulated waters along the Atlantic and Gulf coasts. Reviact™ Multi Omega also includes alpha linolenic acid from vegetable fats such as flaxseed. DHA (Docosahexaenoic Acid) and EPA (Eicosapentaenoic Acid) are the most important anti-inflammatory fatty acids. They are also important building blocks for healthy cell membrane structure. The mechanism of action of omega-3 fatty acid is to inhibit the conversion of arachidonic acid (AA). AA is an omega-6 fatty acid producing prostaglandins, leukotrienes, and thromboxanes. These eicosanoids have predominantly vasoactive and proinflammatory effects. Inhibiting the conversion of AA to these eicosanoids is the principal action of most NSAIDs used to treat OA. Eicosanoids produced from EPA and DHA are not potent inflammatory mediators, in contrast to those produced from AA.

Bromelain is a popular natural remedy for swelling or inflammation, especially of the sinuses and following injury or surgery. Research on mice suggests that bromelain can reduce allergic sensitization and allergic airway disease thanks to its anti-inflammatory and anti-allergic properties. Bromelain is only one of the beneficial nutrients found in pineapples, which also provide vitamin C (helps promote collagen formation and improve iron absorption, among other functions) and manganese (supports metabolism and bone density).It has been shown to be anti-inflammatory and been used to treat inflammatory conditions like arthritis. Bromelain seems to cause the body to produce substances that fight pain and swelling (inflammation).

Alpha Lipoic Acid may be recommended to promote ocular (eye) health and to help slow degenerative neurological conditions. Increased fatty acid intake, especially Omega fatty acids, and increased zinc intake helps maintain healthy skin and coat and may modulate inflammatory reactions. The antioxidant properties of alpha-lipoic acid have been linked to several benefits, including lower blood sugar levels, reduced inflammation, improves skin’s quality and improved nerve function.

A potent antioxidant, vitamin C protects your cells from damage, reduces the severity of allergic reactions and helps your body to fight infections. When taken during allergy season, vitamin C can slow down the overreaction of your body to environmental triggers by decreasing your body's histamine production.

Chronic inflammation produces significant numbers or reactive oxygen species. NAC is used to counter the damaging effects of inflammation; particularly where delicate and vital organs are being damaged. One example is the use of NAC to help prevent oxidative damage to the spinal cord in degenerative myelopathy in dogs. N-acetyl cysteine (NAC) is a supplement form of cysteine. Consuming adequate cysteine and NAC is important for a variety of health reasons — including replenishing the most powerful antioxidant in your body, glutathione. These amino acids also help with chronic respiratory conditions, fertility and brain health.

New research has focused on the health benefits of short-chain fructooligosaccharides (scFOS), which are low-calorie, non-digestible carbohydrates that can improve food taste and texture while aiding immunity, bone health and the growth and balance of important bacteria in the digestive track. A recent review in Acta Cirurgica Brasileira found that FOS can reduce cholesterol levels in animal studies. Introducing FOS into a calorie-restricted diet also helped these animals to reduce weight gain.

It also has an anti-inflammatory effect that can help stimulate your skin's healing processes. Vitamin B complex acts as a co-enzyme promoting biochemical reactions to change carbohydrates into glucose providing energy to the body. It is necessary in a dog's diet for the assimilation of protein and fat. Water soluble, this set of vitamins flushes through the body in four to eight hours.

Most dogs with seasonal allergies have either taken antibiotics or steroids at some point to control their allergies. This is a bioflavonoid and is often referred to as ‘nature’s Benadryl’. This supplement is usually paired with bromelain and is thought to have synergistic effects when used together.

probiotics, it's a good idea to look for those which contain bacteria that has shown to be effective for treating allergy and allergic rhinitis. Lactobacillus GG and L. gasseri are believed to be two of the best probiotics for allergies, along with L. acidophilus and Bifidobacterium lactis.

Specific forms and doses of AG increased white blood cell, neutrophil and eosinophil concentrations. Arabinogalactan is a unique dietary fiber that affects the digestive physiology and immunological characteristics of dogs. It helps maintain proper gut flora and boosts the immune system. Promote the growth of probiotic bacteria such as Lactobacilli and bifidobacterial in the intestines, which are important for GI tract health. -Support proper immune system function. The benefits of arabinogalactan, once its fermented in the dog’s gut, is quite impressive: It goes to work in protecting the dog’s intestines against viruses and bacteria.

With its naturally occurring antihistamine properties it helps as a decongestant and with its anti-inflammatory properties eases itching. Within the turmeric spice lies a miraculous compound called ‘Curcumin’. This compound, found in several other plants, has been extensively researched. The reason It has been found to possess anti-inflammatory properties that can relieve swelling and pain as effectively as ibuprofen or aspirin. These medicinal properties are crucial in assisting us to care for our aging canines; Arthritis, the thinning of cartilage between bones and joints can cause excruciating pain. Turmeric helps relieve this pain in a natural way without worrying about toxic side-effects that can accompany pharmaceutical solutions. That way, they will be able to keep playing with you even as they grow older!

Ginger has lots of benefits like Soothes burns and blisters, Radiant skin, Skin toning, Hypopigmented (white) scars, reduces hair loss, Stimulates hair growth. It acts as an anti-inflammatory that can reduce pain. Ginger contains gingerol, which has been shown in lab tests to relieve the pain associated with arthritis by preventing inflammation and joint destruction. One potential use for ginger in small animals is in the relief or prevention of gastric dilatation and volvulus (GDV or bloat) in dogs. Despite its efficacy in preventing vomiting, ginger has been shown to stimulate stomach motility and accelerate stomach emptying time in multiple studies. The most well-known medical use of ginger is as an anti-emetic (prevention of nausea and vomiting).

Atopic dermatitis affects 3-15% of the general dog population and it has been diagnosed by veterinarians up to 58% of dogs affected with skin disease. It is usually a life-long pathology which can be controlled, but it can be seldom cured. The present investigation describes a case study in which lactoferricin and verbascoside are part of a formulation to obtain a dermatological lotion for canine dermatitis treatment. During treatment period the total clinical score progressively decreased associated with an improvement in clinical signs. No adverse effects were reported in any of the treated dogs. The present research suggests that daily applications of tested emulsion are effective in reducing bacterial overgrowth and clinical signs in skin folds and atopic dermatitis.